At the moment, there are two styles of experiments on itaconate: Irg1−/− macrophages plus the regulatory impact of itaconate derivatives. Both of these final results ended up complementary and uncovered which the regulatory mechanisms of itaconate involved alkylation on Keap1 to activate Nrf2, succinate dehydrogenase inhibition, activating transcription factor 3 https://cdk9in768024.blogproducer.com/36199616/the-best-side-of-bms-202